The interaction effects of antihypertensives on the fall risk of antidepressant users among older adults, 1 + 1 = 3?

Abstract

Objective: Falling is a problem for older adults and a public health concern worldwide. Many factors could potentially increase fall risk. The use of medication and drug-drug interactions are two factors that potentially increase fall risk. This study aimed to investigate the possible (interaction) effects of the use of antihypertensives on the fall risk of antidepressant users.

Conclusion: There was no significant interaction effect from the use of antihypertensives on the fall risk of antidepressant users. More investigation is needed on this topic among subgroups of antihypertensives and their possible interaction effect on the fall risk of antidepressant users.